We are in the matrix man...
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Originally posted by 78X View PostReaction of the normal isomer of [B20H18]2− and the protected thiol anion, [SC(O)OC(CH3)3]−, produces an unexpected isomer of [B20H17SC(O)OC(CH3)3]4− directly and in good yield. The isomer produced under mild conditions is characterized by an apical–apical boron atom intercage connection as well as the location of the thiol substituent on an equatorial belt adjacent to the terminal boron apex. Although the formation of this isomer from nucleophilic attack of the normal isomer of [B20H18]2− has not been reported previously, the isomeric assignment has been unambiguously confirmed by one-dimensional and two-dimensional 11B NMR spectroscopy. Deprotection of the thiol substituent under acidic conditions produces a protonated intermediate, [B20H18SH]3−, which can be deprotonated with a suitable base to yield the desired product, [B20H17SH]4−. The sodium salt of the resulting [B20H17SH]4− ion has been encapsulated in small, unilamellar liposomes, which are capable of delivering their contents selectively to tumors in vivo, and investigated as a potential agent for boron neutron capture therapy. The biodistribution of boron was determined after intravenous injection of the liposomal suspension into BALB/c mice bearing EMT6 mammary adenocarcinoma. At low injected doses, the tumor boron concentration increased throughout the time-course experiment, resulting in a maximum observed boron concentration of 46.7 μg of B per g of tumor at 48 h and a tumor to blood boron ratio of 7.7. The boron concentration obtained in the tumor corresponds to 22.2% injected dose (i.d.) per g of tissue, a value analogous to the most promising polyhedral borane anions investigated for liposomal delivery and subsequent application in boron neutron capture therapy.
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Originally posted by Big A View PostI don't think that it ever would, just the opposite actually. Miscreants would continue to breed, pass along their genes and immoral natures, and take out the good people that don't wish harm upon others. Even moral people would have to adjust to protect themselves and their family, and eventually become only a step above the said miscreants.
What good is absolute freedom if you can't enjoy it for fear of harm?
it'll get a lot better awful quick
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Originally posted by Cooter View Posthorse shit... you quit taking money from hard working, moral people and paying people to pump out inbred future-convicts... you make it legal to kill for any sort of theft... you kill or excommunicate every treasonous politician who has spit on the constitution they swore to uphold...
it'll get a lot better awful quick
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Originally posted by Denny View PostWe both know that is asking too much.
I have zero faith in humanity on a whole. Which is why I refuse to bring another person into this shit hole and why I refuse to conform to somebody else's illogical mold
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Without laws and repercussions it would be anarchy. I rather not be forced to live where my family is at the mercy of troops of 'katrina victims' running rampant.You cannot kill them all, numbers win, and stupidity breeds faster and is easily controlled.
StevoOriginally posted by SSMAN...Welcome to the land of "Fuck it". No body cares, and if they do, no body cares.
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Originally posted by stevo View PostWithout laws and repercussions it would be anarchy. I rather not be forced to live where my family is at the mercy of troops of 'katrina victims' running rampant.You cannot kill them all, numbers win, and stupidity breeds faster and is easily controlled.
Stevo
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